Tympanogen, Inc. develops innovative ear, nose, and throat devices based on proprietary gel technology. The first product, Perf-Fix, will transform traditional tympanoplasty procedures into a quick office visit.

Perf-Fix can be applied in an office setting within 10 minutes, without general anesthesia or margin freshening. This gel patch encourages regeneration of the full tympanic membrane structure at the same high success rates of traditional tympanoplasty.

Perf-Fix is still in development, and is not yet for sale.


Tympanogen was founded in 2014 by a dynamic and energetic team of engineers and physicians dedicated to simplifying medical procedures and reducing healthcare costs. The company operates out of the VA Bio+Tech Park in Richmond, VA.

Elaine Horn-Ranney, PhD

President & Chief Executive Officer

Elaine Horn_Ranney,PHD

Dr. Horn-Ranney has led the Tympanogen team since the company’s inception in 2014. During this time Tympanogen won multiple business plan competitions as well as federal and state grant funds. She possesses a robust knowledge of biomaterials and is experienced in synthesizing materials for tissue engineering and regenerative medicine applications, with a specialized focus on translating laboratory research into clinical products. Dr. Horn-Ranney received both her BSE and PhD in Biomedical Engineering from Tulane University, currently serves on the Board of Directors for the Virginia Biotechnology Association, and is an Adjunct Professor at Old Dominion University.

Parastoo Khoshakhlagh, PhD

Senior Vice-President & Chief Scientific Officer

Parastoo Khoshakhlagh, MS

Dr. Khoshakhlagh has over 10 years experience in the development, characterization, and evaluation of biomaterials in animal and cellular models, and leads manufacturing efforts for Tympanogen. She completed a postdoctoral fellowship in Dr. Ali Khademhosseini’s laboratory at Harvard-MIT Department of Science and Technology, and is currently a postdoctoral fellow in Dr. George Church’s laboratory at Harvard Medical School. Dr. Khoshakhlagh received her BS in Materials Science from Iran University of Science and Technology, her MS in Biomedical Engineering from Amirkabir University of Technology, and her PhD in Biomedical Engineering from Tulane University. She was the core scientist of Medicogen, the first-place winner of the 2013 Breast Cancer Startup Challenge.

Jesse Ranney, MD

Chief Medical Officer

Jesse Ranney, MD

Dr. Ranney is a pediatrician at Sentara Williamsburg Regional Hospital who actively identifies clinical issues that can be resolved with material therapies while guiding product development toward a physician-friendly format. Dr. Ranney originated the idea of using hydrogels, developed by the Tympanogen team, to replace autologous grafts in eardrum repair. He received his BS in Biomedical Engineering from Tulane University, his MD from Louisiana State University, and completed his pediatrics residency training at EVMS/CHKD.


Arthur Coury, PhD

  • Professor, Northeastern University
  • Independent medical devices consultant
Arthur Coury, PhD

Barry Strasnick, MD, FACS

  • Chairman of the Department of Otolaryngology
  • Eastern Virginia Medical School
Barry Strasnick, MD


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Tympanogen moves to the VA Bio+Tech Park

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